Research
Research
My research focuses on developing active and intelligent medical systems that can navigate complex biological environments, respond to local physiological conditions, and perform therapeutic functions inside the body. Across medical micro/nanorobotics, in vivo biofabrication, and nanomedicine, I seek to control how engineered materials are transported, localized, and activated within biological systems. The long-term goal is to advance these technologies toward clinical translation for precise, minimally invasive, and patient-specific therapeutic intervention.
Medical Micro/Nanorobots
Medical micro- and nanorobotic systems provide new approaches for active transport, targeted delivery, and minimally invasive therapy. A major challenge in this area is overcoming biological barriers that limit conventional drug delivery, including vascular barriers, dense tissue microenvironments, and restricted tissue interfaces. Responsive materials, physical actuation, molecular targeting, and imaging-guided evaluation can improve transport, localization, and therapeutic control within the body. My interest is in developing micro/nanorobotic systems that can navigate complex biological environments, respond to physiological conditions, and provide localized therapeutic functions.
In Vivo Biofabrication
Imaging-guided in vivo biofabrication aims to construct functional biomaterials directly within target tissues through minimally invasive approaches. Current tissue engineering strategies often rely on ex vivo fabrication followed by surgical implantation, which can limit their adaptability to deep, irregular, moving, and patient-specific tissue environments. Focused ultrasound provides a means to control material formation within biological tissues, together with responsive bioinks and image-guided printing. I am particularly interested in developing in vivo fabrication methods that can adapt to complex anatomy and tissue motion for precise formation of functional biomaterials.
Nanomedicine and Biointerfaces
Nanomedicine and biointerface research provides a foundation for designing materials that function effectively within biological systems. Nanomaterial properties such as composition, morphology, surface chemistry, and biodegradability can strongly influence biological transport, cellular interactions, imaging performance, and therapeutic activity. Biodegradable nanomaterials, molecular imaging, responsive nanosensors, and engineered material interfaces provide useful tools for controlling these interactions. My interest is in designing functional nanomaterials that can respond to biological environments and support precision diagnosis, therapy, and broader applications in micro/nanorobotics and in vivo biofabrication.