Publications

† Equal contribution     * Corresponding author

2026

  1. Photothermally gated nanorobots for active blood-brain barrier transcytosis and brain delivery
    Jounghyun Yoo†, Suhyun Kim†, Woojung Yoo, Hong Han, Gwangmook Kim, Abel Worku Tessema, Seohyun Kim, Songsong Tang, Junyoung Kim, Hung Dong Truong, Xiaotian Ma, Gunho Kim, Sukyoung Won, Jeong-Won Choi, Joonseup Hwang, Jeongmin Oh, Yein Seok, Jun Ki Kim, HyungJoon Cho, Tae-Eun Park, Jinmyoung Joo, and Wei Gao
    Science Robotics, 2026
    Under revision
  2. Programmable multigas cancer therapy using ultrasound-propelled microrobots
    Hong Han†, Xiaotian Ma†, Jounghyun Yoo†, Songsong Tang, Kaidi Zhao, Ernesto Criado-Hidalgo, H. D. Truong, Camilla Fezzi, Junhang Zhang, Gong Chen, C. Hays, R. J. Reyes Segura, Zhaoqian Jin, A. Liu, Mikhail G. Shapiro, Julia R. Greer, Qifa Zhou, and Wei Gao
    Nature Communications, 2026
    Under revision
  3. Bridging the barrier: Micro- and nanorobotics for active brain delivery
    Jounghyun Yoo, Jinmyoung Joo, and Wei Gao
    Matter, 2026
    In press
    DOI
  4. Enzymatic microbubble robots
    Songsong Tang, Hong Han, Xiaotian Ma, Payal N. Patel, Chen Gong, Junhang Zhang, Ernesto Criado-Hidalgo, Jounghyun Yoo, Jiahong Li, Gwangmook Kim, Mikhail G. Shapiro, Qifa Zhou, and Wei Gao
    Nature Nanotechnology, 21, 397, 2026
    DOI
  5. Directed and rapid intracellular delivery of CRISPR/Cas9 ribonucleoproteins using charge-reversible fusogenic nanoparticles for therapeutic genome editing
    Minjong Kim, Kyunghwan Kim, Jihyun Lee, Soo Ah Park, Euihwan Jeong, Song-Yi Choi, Taejoon Kwon, Kyungjae Myung, Jounghyun Yoo*, Seung Woo Cho*, and Jinmyoung Joo*
    Small, 22, e11362, 2026
    Featured on Journal Cover
    DOI

2025

  1. Surface-engineered nanobeads for regioselective antibody binding: A robust immunoassay platform leveraging catalytic signal amplification
    Jounghyun Yoo†, Youngsun Kim†, Ji Hyun Back†, Jawon Shin, Pan Kee Bae, Kyung Mi Park, Myung Kim, Young Hun Seo, Yecheol Bak, Yoon Ho Heo, Jeongyun Heo, Honghwan Choi, Yongju Kim, Sangyoup Lee, Ji Eun Lee, Sohdam Jeong, Jin-Kyoung Yang, and Sehoon Kim
    Biosensors and Bioelectronics, 281, 117463, 2025
    DOI
  2. Imaging-guided deep tissue in vivo sound printing
    Elham Davoodi, Jiahong Li, Xiaotian Ma, Alireza Hassani Najafabadi, Jounghyun Yoo, Gengxi Lu, Ehsan Shirzaei Sani, Sunho Lee, Hossein Montazerian, Gwangmook Kim, Jee Won Yang, Jason Williams, Yushun Zeng, Lei S. Li, Zhiyang Jin, Behnam Sadri, Shervin S. Nia, Lihong V. Wang, Tzung K. Hsiai, Paul S. Weiss, Qifa Zhou, Ali Khademhosseini, Di Wu, Mikhail G. Shapiro, and Wei Gao
    Science, 388, 616–623, 2025
    DOI
  3. All-printed chip-less wearable neuromorphic system for multimodal physiochemical heath monitoring
    Yongsuk Choi, Peng Jin, Sanghyun Lee, Yu Song, Roland Yingjie Tay, Gwangmook Kim, Jounghyun Yoo, Hong Han, Jeonghee Yeom, Jeong Ho Cho, Donghwan Kim, and Wei Gao
    Nature Communications, 16, 5689, 2025
    DOI
  4. Sustained release of HIF-2α inhibitors using biodegradable porous silicon carriers for enhanced immunogenic cell death of malignant Merkel cell carcinoma
    Juyoung Seong, Minju Kim, Jounghyun Yoo, David L. Mack, Jung Hyun Lee, and Jinmyoung Joo
    ACS Applied Materials & Interfaces, 17, 7449, 2025
    DOI

2024

  1. Photonic control of ligand nanospacing in self-assembly regulates stem cell fate
    Sungkyu Lee†, Jounghyun Yoo†, Gunhyu Bae, Ramar Thangam, Jeongyun Heo, Jung Yeon Park, Honghwan Choi, Chowon Kim, Jusung An, Jungryun Kim, Kwang Rok Mun, Seungyong Shin, Kunyu Zhang, Pengchao Zhao, Yoonji Kim, Nayeon Kang, Seong-Beom Han, Dahee Kim, Jiwon Yoon, Misun Kang, Jihwan Kim, Letao Yang, Solmaz Karamikamkar, Jinjoo Kim, Yangzhi Zhu, Alireza Hassani Najafabadi, Guosheng Song, Dong-Hwee Kim, Ki-Bum Lee, Soong Ju Oh, Hyun-Do Jung, Hyun-Cheol Song, Woo Young Jang, Liming Bian, Zhiqin Chu, Juyoung Yoon, Jong Seung Kim, Yu Shrike Zhang, Yuri Kim, Ho Seong Jang, Sehoon Kim, and Heemin Kang
    Bioactive Materials, 34, 164–180, 2024
    DOI
  2. Imaging-guided bioresorbable acoustic hydrogel microrobots
    Hong Han, Xiaotian Ma, Weiting Deng, Junhang Zhang, Songsong Tang, On Shun Pak, Lailai Zhu, Ernesto Criado-Hidalgo, Chen Gong, Emil Karshalev, Jounghyun Yoo, Ming You, Ann Liu, Canran Wang, Hao Shen, Payal N. Patel, Claire L. Hays, Peter J. Gunnarson, Lei Li, Yang Zhang, John O. Dabiri, Lihong V. Wang, Mikhail G. Shapiro, Di Wu, Qifa Zhou, Julia R. Greer, and Wei Gao
    Science Robotics, 9, eadp3593, 2024
    DOI
  3. Bacterial outer membrane vesicle nanorobot
    Songsong Tang, Daitian Tang, Houhong Zhou, Yangyang Li, Dewang Zhou, Xiqi Peng, Chunyu Ren, Yilin Su, Shaohua Zhang, Haoxiang Zheng, Fangchen Wan, Jounghyun Yoo, Hong Han, Xiaotian Ma, Wei Gao, and Shaochen Wu
    Proceedings of the National Academy of Sciences, 121, e2403460121, 2024
    DOI
  4. Room-temperature phosphorescence of defect-engineered silica nanoparticles for high-contrast afterglow bioimaging
    Heemin Chang, Yoonsang Park, Kyunghwan Kim, Chaewon Han, Yeongjun Yoon, Woojung Yoo, Jounghyun Yoo, Dajin Lee, Hyunho Han, Kyeounghak Kim, Jinmyoung Joo, and Woosung Kwon
    Chemical Engineering Journal, 493, 152529, 2024
    DOI

2023

  1. Micro- and nanorobots for biomedical applications in the brain
    Jounghyun Yoo†, Songsong Tang†, and Wei Gao
    Nature Reviews Bioengineering, 1, 308, 2023
    DOI

2022

  1. Tailored polyethylene glycol grafting on porous nanoparticles for enhanced targeting and intracellular siRNA delivery
    Jounghyun Yoo†, Kyunghwan Kim†, Suhyun Kim, Hee Ho Park, Heungsoo Shin, and Jinmyoung Joo
    Nanoscale, 14, 14482–14490, 2022
    Featured on Journal Cover
    DOI
  2. Multifunction-harnessed afterglow nanosensor for molecular imaging of acute kidney injury in vivo
    Tikum Florence Anjong†, Honghwan Choi†, Jounghyun Yoo†, Yecheol Bak, Yuri Cho, Dojin Kim, Seokyung Lee, Kangwon Lee, Bong-Gi Kim, and Sehoon Kim
    Small, 18, 2200245, 2022
    DOI
  3. Photoswitchable microgels for dynamic macrophage modulation
    Yuri Kim, Ramar Thangam, Jounghyun Yoo, Jeongyun Heo, Jung Yeon Park, Nayeon Kang, Sungkyu Lee, Jiwon Yoon, Kwang Rok Mun, Misun Kang, Sunhong Min, Seong Yeol Kim, Subin Son, Jihwan Kim, Hyunsik Hong, Gunhyu Bae, Kanghyeon Kim, Sanghyeok Lee, Letao Yang, Ja Yeon Lee, Jinjoo Kim, Steve Park, Dong-Hyun Kim, Ki-Bum Lee, Woo Young Jang, Bong Hoon Kim, Ramasamy Paulmurugan, Seung-Woo Cho, Hyun-Cheol Song, Seok Ju Kang, Wujin Sun, Yangzhi Zhu, Junmin Lee, Han-Jun Kim, Ho Seong Jang, Jong Seung Kim, Ali Khademhosseini, Yongju Kim, Sehoon Kim, and Heemin Kang
    Advanced Materials, 34, 2205498, 2022
    Featured on Journal Cover
    DOI
  4. Direct deposition of anatase TiO2 on thermally unstable gold nanobipyramid: Morphology-conserved plasmonic nanohybrid for combinational photothermal and photocatalytic cancer therapy
    Dohyub Jang, Subin Yu, Kyungwha Chung, Jounghyun Yoo, Filipe Marques Mota, Jianfang Wang, Dong June Ahn, Sehoon Kim, and Dong Ha Kim
    Applied Materials Today, 27, 101472, 2022
    DOI

2021

  1. Metal complexation-mediated stable and biocompatible nanoformulation of clinically approved near-infrared absorber for improved tumor targeting and photonic theranostics
    Yong-Deok Lee†, Hyeon Jeong Shin†, Jounghyun Yoo†, Gunho Kim, Min-Kyoung Kang, Jae Jun Lee, Joona Bang, Jin-Kyoung Yang, and Sehoon Kim
    Nano Convergence, 8, 1, 2021
    DOI
  2. Photoechogenic inflatable nanohybrids for upconversion-mediated sonotheranostics
    Keunsoo Jeong, Dojin Kim, Hyun Jun Kim, Yong-Deok Lee, Jounghyun Yoo, Dohyub Jang, Seokyung Lee, Hyeonjong Park, Youngsun Kim, Ajay Singh, Dong June Ahn, Dong Ha Kim, Joona Bang, Jungahn Kim, Paras N. Prasad, and Sehoon Kim
    ACS Nano, 15, 18394, 2021
    DOI
  3. Superoxide-responsive fluorogenic molecular probes for optical bioimaging of neurodegenerative events in Alzheimer’s disease
    Jawon Shin, Dong Min Kang, Jounghyun Yoo, Jeongyun Heo, Keunsoo Jeong, Ji Hyung Chung, Ye Sun Han, and Sehoon Kim
    Analyst, 146, 4748, 2021
    Featured on Journal Cover
    DOI

2020

  1. Biocompatible organosilica nanoparticles with self-encapsulated phenyl motifs for effective UV protection
    Jounghyun Yoo†, Hyemin Kim†, Heemin Chang†, Wonchan Park, Sei Kwang Hahn, and Woosung Kwon
    ACS Applied Materials & Interfaces, 12, 9062–9069, 2020
    DOI

2019

  1. A multi-dye containing MOF for the ratiometric detection and simultaneous removal of Cr2O7(2-) in the presence of interfering ions
    Jounghyun Yoo†, UnJin Ryu†, Woosung Kwon, and Kyung Min Choi
    Sensors and Actuators B: Chemical, 283, 426–433, 2019
    DOI
  2. Photoluminescent and biodegradable porous silicon nanoparticles for biomedical imaging
    Yoonsang Park†, Jounghyun Yoo†, Myoung-Hee Kang*, Woosung Kwon, and Jinmyoung Joo
    Journal of Materials Chemistry B, 7, 6271–6292, 2019
    Featured on Journal Cover
    DOI
  3. Controlled growth of silica nanoparticles using two-phase orthogonal solvents for bioimaging
    Heemin Chang†, Jounghyun Yoo†, Hyemin Kim, Wonchan Park, Sei Kwang Hahn, and Woosung Kwon
    Journal of Luminescence, 214, 116529, 2019
    DOI
  4. Formation of TiO2@carbon core/shell nanocomposites from single molecular layer of aromatic compounds for photocatalytic hydrogen peroxide generation
    Taehyung Lee, Hoang Tran Bui, Jounghyun Yoo, Mirae Ra, Seung Hwan Han, Wooyul Kim, and Woosung Kwon
    ACS Applied Materials & Interfaces, 11, 41196–41203, 2019
    DOI

2018

  1. Defect-induced fluorescence of silica nanoparticles for bioimaging applications
    Jounghyun Yoo†, Seulgi Han†, Wonchan Park, Taehyung Lee, Yoonsang Park, Heemin Chang, Sei Kwang Hahn, and Woosung Kwon
    ACS Applied Materials & Interfaces, 10, 44247–44256, 2018
    DOI
  2. In vivo photoacoustic imaging of livers using biodegradable hyaluronic acid-conjugated silica nanoparticles
    Donghyun Lee†, Songeun Beack†, Jounghyun Yoo†, Su-Kyoung Kim, Changho Lee, Woosung Kwon, Sei Kwang Hahn, and Chulhong Kim
    Advanced Functional Materials, 28, 1800941, 2018
    Featured on Journal Cover
    DOI

2017

  1. Tailoring nanocrystalline metal-organic frameworks as fluorescent dye carriers for bioimaging
    UnJin Ryu†, Jounghyun Yoo†, Woosung Kwon, and Kyung Min Choi
    Inorganic Chemistry, 56, 12859–12865, 2017
    DOI

2016

  1. Improving functionality of carbon nanodots: Doping and surface functionalization
    Yoonsang Park†, Jounghyun Yoo†, Boram Lim, Woosung Kwon, and Shi-Woo Rhee
    Journal of Materials Chemistry A, 4, 11582–11603, 2016
    DOI